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2021-07-14 00:38:47 <hololeap> every person has exactly two biological parents... is that a reasonable enough assumption?
2021-07-14 00:39:11 falafel joins (~falafel@pool-96-255-70-50.washdc.fios.verizon.net)
2021-07-14 00:40:46 <geekosaur> for genetics yes, for other aspects no
2021-07-14 00:41:11 <geekosaur> and the biological parents may be unrelated to the familial parents
2021-07-14 00:41:46 <hololeap> That's why I specified _biological_ parents
2021-07-14 00:42:09 <hololeap> I'd be interested in hearing of a case where someone didn't have exactly two biological parents
2021-07-14 00:42:15 <hololeap> cloning?
2021-07-14 00:42:43 <hololeap> someone = an individual of the homo-sapeins species
2021-07-14 00:43:32 <geekosaur> actually davean's earlier comment implied unexpected complexity
2021-07-14 00:44:35 <hololeap> I understand that it wouldn't necessarily make a nice binary tree all the way up, but I'm wondering if we can at least hold it as axiomatic that each individual has exactly two biological parents
2021-07-14 00:45:37 <davean> geekosaur: well, consider if you had an egg donated, but used the birthing mother's nucleus with some male's sperm. We're up to 3 now. And that differs mitocondrially
2021-07-14 00:45:44 <davean> geekosaur: Thats a simple case
2021-07-14 00:45:55 <geekosaur> was considering raising that case
2021-07-14 00:46:03 × MQ-17J quits (~MQ-17J@d14-69-206-129.try.wideopenwest.com) (Ping timeout: 255 seconds)
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2021-07-14 00:46:16 <hololeap> I would think the egg and sperm donors would be the two in that case
2021-07-14 00:46:42 <davean> hololeap: nope, the nucleous provide's materal DNS also
2021-07-14 00:46:57 <davean> You've got 3 clear DNA sources
2021-07-14 00:47:05 <davean> all providing seperate DNA
2021-07-14 00:47:19 <hololeap> I guess you could argue that the blood from the surrugate mother would be in the fetus as well
2021-07-14 00:47:31 <davean> No, no, I'm talking clearer than that here
2021-07-14 00:47:48 <davean> I wasn't even talking about a surrugate - though that can matter also of course
2021-07-14 00:47:53 <davean> also, can I remind you of chimeras?
2021-07-14 00:48:01 <hololeap> lol
2021-07-14 00:48:26 <davean> They happen
2021-07-14 00:48:43 <davean> ANYWAY, parents are complicated
2021-07-14 00:49:05 <hololeap> I'm definitely not trying to mock... but what do you mean by chimeras?
2021-07-14 00:49:22 <davean> hololeap: chimeras are where multiple zygotes merge and form one individual
2021-07-14 00:49:42 <hololeap> oh... ok. I thought you meant like a human-animal hybrid
2021-07-14 00:49:50 <davean> No, its a human-human hybrid
2021-07-14 00:49:56 <davean> So maybe you're you, but your liver is your unborn sister.
2021-07-14 00:49:57 MQ-17J joins (~MQ-17J@8.21.10.15)
2021-07-14 00:50:15 <davean> Or maybe your unborn half brother
2021-07-14 00:50:16 <hololeap> No, I've never heard of that and that's really interesting
2021-07-14 00:50:46 <davean> Look, this is REALLY complicated. And some politicans got together and decided what data would go on the forms
2021-07-14 00:50:59 <davean> :)
2021-07-14 00:51:03 <davean> The best way to make a standard
2021-07-14 00:51:16 <hololeap> fair enough. I just wanted to find a model that would make sense, but it sounds like it can get really bizarre
2021-07-14 00:51:27 <davean> REALLY bizar
2021-07-14 00:51:52 <davean> You could have mitocondria from one person, male and female donated from 2 others, and be a chimera
2021-07-14 00:51:54 <davean> Who the fuck knows
2021-07-14 00:52:09 <hololeap> where can I read more about this?
2021-07-14 00:52:26 <davean> Uh, no idea
2021-07-14 00:52:35 <davean> https://en.wikipedia.org/wiki/Chimera_(genetics) has a section on human chimeras
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2021-07-14 00:52:47 <davean> the first example has shown up in IVF
2021-07-14 00:53:13 <davean> uh, I only know about this because I had to descamble genetics databases for a genetics lab information management tool back in the day
2021-07-14 00:53:35 <hololeap> that's cool. you have first-hand evidence
2021-07-14 00:54:20 <davean> oh huh, wikipedia says, after I got out of this, there DID become human-animal chimeras
2021-07-14 00:54:23 <davean> well thats a thing
2021-07-14 00:54:38 <davean> So yah, your parents might even be different species I guess
2021-07-14 00:54:44 <davean> Thats even more complicated than I knew of!
2021-07-14 00:55:19 <davean> hololeap: oh this actually suggests a REALLY simple case I didn't even think of! Organ donation
2021-07-14 00:55:30 <davean> I mean not what people generally mean here, but in a medical sense it matters
2021-07-14 00:58:23 <davean> hololeap: https://www.statnews.com/2019/01/24/first-trial-of-three-person-ivf-for-infertility/ here is the origional case I listed, or a way it happens
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2021-07-14 00:58:49 <davean> I don't know how much you know about biology, I was guessing not much sine the initial example seemed to miss, but that could be how I said it
2021-07-14 00:59:07 <davean> basicly mitochondria are seperate "sub cells" with their own genetics
2021-07-14 00:59:28 <davean> seperate from what you generally think of as "your DNA" from your basic bio classes in HS
2021-07-14 00:59:57 <davean> and its purely matrolineal (under normal circumstances! One COULD swap them out from the father of course if done on purpose!)
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2021-07-14 01:18:11 <hololeap> I'm not that familiar with that level of human biology, mostly just the basic stuff that you mentioned from HS. I know a bit more about botany and I know that can get really bizarre as well
2021-07-14 01:18:34 <yin[m]> this is hilariously creepy https://www.youtube.com/watch?v=Kw0AEtrr7E0
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2021-07-14 01:27:25 <hololeap> davean: I thought of organ donation after you mentioned the possibility of my liver being from a different zygote, and it ties into that whole philosophical dilemma of when a person stops being human after N bionic body replacements
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2021-07-14 01:28:04 <davean> stops being human? I'd think the question would be when they stop being the same human
2021-07-14 01:28:28 <geekosaur> "bionic"
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2021-07-14 01:29:32 <hololeap> there's a futurama episode that goes into this :)
2021-07-14 01:29:34 <geekosaur> kinda odd to consider a human in the context of the ship of Theseus
2021-07-14 01:30:07 <davean> geekosaur: I don't find it odd at all - or I find it odd to consider a person is the same person over any period of time thats non-negligable
2021-07-14 01:30:28 <davean> if someone doesn't change, they're not really worth considering much of a person, are they?
2021-07-14 01:30:53 <davean> if they don't act, or think like they did, how would you determin they're the same?
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2021-07-14 01:31:08 <geekosaur> I'm actually on your side of that argument, but their body parts have continuity even though they have changed
2021-07-14 01:31:19 <geekosaur> (cells already do the ship of theseus thing)
2021-07-14 01:31:32 <nshepperd> a human is the squishy thing in the skull. the rest is just scaffolding
2021-07-14 01:32:46 <hololeap> I read about cases of people taking on their donors memories after getting an organ transplant... not sure if it's true or not, but interesting to consider nonetheless

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